Pilot Project 3
Novel Formulation of Synthetic Retinoid
African American women have higher incidence of breast cancer before the age of 40, and more severe disease at all ages. In particular, African American women also have the highest breast cancer death rate among all racial and ethnic groups and are 40% more likely to die of breast cancer than Caucasian women. This health disparity is attributed to a number of factors including higher rates of early onset, more advanced disease stage at diagnosis, and a higher prevalence of estrogen receptor-negative breast cancer (ENBC) and the more aggressive cancer subtype of triple-negative breast cancer (TNBC). Currently, there are no targeted prevention for ENBC and TNBC. This research will focus on developing a highly effective, low-toxic, easily compliable topical preventive therapy for preventing ENBC and TNBC development in mouse models. The outcomes from this research will directly address the cancer prevention disparities in high-risk African-American women.
Interested in participating in a breast cancer study?
UHAND PI, Dr. Lorraine R Reitzel and UHAND Affiliate Dr. Shahnjayla K. Connors, are recruiting African American women breast cancer survivors for “A Patient-Centered Approach to Exploring Breast Reconstruction in African American Women,” which focuses on exploring breast reconstruction determinants and decision-making in African-American breast cancer survivors.
At the end of this study, the resulting breast reconstruction decision-making conceptual framework will be used to inform the development and dissemination of culturally-competent interventions to ensure equitable access to breast reconstruction for African-American women. For more details please click the button below to download a flyer on how to participate!